YAP/TAZ-TEAD link angiogenesis to nutrients

Roxana E Oberkersch & Massimo M. Santoro. Nat Metab. PMID: 35726025

A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells

Brian G Coon, Sushma Timalsina, Matteo Astone, Zhen W Zhuang, Jennifer Fang, Jinah Han, Jurgen Themen, Minhwan Chung, Young Joo Yang-Klingler, Mukesh Jain, Karen K Hirschi, Ai Yamamato, Louis-Eric Trudeau, Massimo M. Santoro, Martin A Schwartz. J Cell Biol PMID: 35695893

Cancer-Induced Metabolic Rewiring of Tumor Endothelial Cells

Jacopo Lidonnici,  Massimo M. Santoro, Roxana E Oberkersch. Cancers (Basel) PMID: 35681715

Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis

Roxana E Oberkersch, Giovanna Pontarin, Matteo Astone, Marianna Spizzotin, Liaisan Arslanbaeva, Giovanni Tosi, Emiliano Panieri, Sara Ricciardi, Maria Francesca Allega, Alessia Brossa, Paolo Grumati, Benedetta Bussolati, Stefano Biffo, Saverio Tardito & Massimo M. Santoro. Development Cell PMID: 35580611

UBIAD1 and CoQ10 protect melanoma cells from lipid peroxidation-mediated cell death

Liaisan Arslanbaeva, Giovanni Tosi, Marco Ravazzolo, Manuela Simonato, Francesco A Tucci, Salvatore Pece, Paola Cogo  & Massimo M. Santoro. Redox Biology PMID: 35255427

Oxidative pentose phosphate pathway controls vascular mural cell coverage by regulating extracellular matrix composition

Nicola Facchinello, Matteo Astone, Matteo Audano, Roxana E. Oberkersch, Marianna Spizzotin, Enrica Calura, Madalena Marques, Mihaela Crisan, Nico Mitro & Massimo M. Santoro. Nature Metabolism PMID: 35102339


LPHN2 inhibits vascular permeability by differential control of endothelial cell adhesion

Chiara Camillo, Nicola Facchinello, Giulia Villari, Giulia Mana, Noemi Gioelli, Chiara Sandri, Matteo Astone, Dora Tortarolo, Fabiana Clapero, Dafne Gays, Roxana E. Oberkersch, Marco Arese, Luca Tamagnone, Donatella Valdembri,  Massimo M. Santoro* and Guido Serini*. Journal of Cell Biology PMID: 34581723

Origin and Mechanisms of Smooth Muscle Cells Development in Vertebrates

Michael Donadon and Massimo M. Santoro. Development PMID: 33789914

Efficient clofilium tosylate-mediated rescue of polg-related disease phenotypes in zebrafish

Nicola Facchinello, Claudio Laquatra, Lisa Locatello, Giorgia Beffagna, Raquel Brañas Casas, Chiara Fornetto, Alberto Dinarello, Laura Martorano, Andrea Vettori, Giovanni Risato, Rudy Celeghin, Giacomo Meneghetti, Massimo M. Santoro, Agnes Delahodde, Francesco Vanzi, Andrea Rasola, Luisa Dalla Valle, Maria Berica Rasotto, Tiziana Lodi, Enrico Baruffini, Francesco Argenton, and Natascia Tiso. Cell Death & Disease PMID: 33469036

Time to fight: targeting the circadian clock molecular machinery in cancer therapy

Matteo Astone and Massimo M. Santoro. Drug Discovery Today PMID: 33549826

Adaptive redox homeostasis in cutaneous melanoma

Liasian Arslanbaeva and Massimo M. Santoro. Redox Biology​  PMID: 33091721


The Antioxidant Role of Non-mitochondrial CoQ10: Mystery Solved! 

Massimo M. Santoro Cell Metabolism PMID: 31951565

Advantages and challenges of cardiovascular and lymphatic studies in zebrafish research

Massimo M. Santoro, Beltrame M., Panáková D., Siekmann A. F. Tiso, N., Venero Galanternik M., Hyun Min Jung and Brant M. Weinstein. Frontiers in Cell and Developmental Biology PMID: 31192207 

Nano-sampling and reporter tools to study metabolic regulation in zebrafish

Thomas Dickmeis, Yi Feng, Maria Caterina Mione, Nikolay Ninov, Massimo M. Santoro, Herman P Spaink, Philipp Gut. Frontiers Cell and Developmental Biology PMID: 30873407


Role of amino acid metabolism in angiogenesis

Roxana E. Oberkersch and Massimo M. Santoro. Vascular Pharmacology PMID: 30423448

Before the Pump

Dougall Norris and Massimo M. Santoro. Arteriosclerosis, Thrombosis, and Vascular Biology PMID: 30571178 


Loss of Pyruvate Kinase M2 Limits Growth and Triggers Innate Immune Signaling in Endothelial Cells

Oliver A. Stone, Mohamed El-Brolosy, Kerstin Wilhelm, Xiaojing Liu, Ana M. Romão, Elisabetta Grillo, Jason K.H. Lai, Stefan Günther, Sylvia Jeratsch, Carsten Kuenne, I-Ching Lee, Thomas Braun, Massimo M. Santoro, Jason W. Locasale, Michael Potente and Didier Y.R. Stainier. Nature Communications  PMID: 33469036

Photobiomodulation at multiple wavelengths differentially modulates oxidative stress in vitro and in vivo

Rupel, K., Zupin, L., Colliva, A., Kamada, A., Poropat, A., Ottaviani, G., Margherita Gobbo, Lidia Fanfoni, Rossella Gratton, Massimo M. Santoro, Roberto Di Lenarda , Matteo Biasotto, and Serena Zacchigna.  Oxidative Medicine and Cellular Longevity PMID: 30534349

LKB1 loss is associated with glutathione deficiency under oxidative stress and sensitivity of cancer cells to cytotoxic drugs and γ-irradiation

NZulato E., Ciccarese F., Agnusdei V., Pinazza M., Nardo G., Iorio E., Curtarello M., Silic-Benussi M., Rossi E, Venturoli C., Panieri E., Santoro M. Massimo, Quintieri L., Ciminale V, Indraccolo S. Biochem Pharmacology PMID: 30222967 

Compound heterozygous loss-of-function mutations in KIF20A are associated with a novel lethal congenital cardiomyopathy in two siblings 

Jacoba J. Louw, Ricardo Nunes Bastos, Xiaowen Chen, Céline Verdood, Anniek Corveleyn, Yaojuan Jia, Jeroen Breckpot, Marc Gewillig, Hilde Peeters, Massimo M. Santoro, Francis Barr, Koenraad Devriendt PLOS Genetics PMID: 2935759

New models to study vascular mural cell embryonic origin: implications in vascular diseases

Sanjay Sinha and Massimo M. Santoro Cardiovascular Research PMID: 29385541

Fashioning blood vessels by ROS signaling and metabolism

Massimo M. Santoro Seminars in Cell & Developmental Biology  PMID: 28800930


Real-time quantification of subcellular H 2 O 2 and glutathione redox potential in living cardiovascular tissues 

Emiliano Panieri, Carlo Milia, and Massimo M. Santoro. Free Radical Biology and Medicine PMID: 28192232 

Data on metabolic-dependent antioxidant response in the cardiovascular tissues of living zebrafish under stress conditions 

Emiliano Panieri and Massimo M. Santoro Data in Brief PMID: 28516138

An exclusive cellular and molecular network governs intestinal smooth muscle cell differentiation in vertebrates 

Dafne Gays, Christopher Hess, Annalisa Camporeale, Ugo Ala, Paolo Provero, Christian Mosimann, Massimo M. Santoro Development PMID: 28049660

Cilia Control Vascular Mural Cell Recruitment in Vertebrates

Xiaowen Chen, Dafne Gays, Carlo Millia, and Massimo M. Santoro Cell Reports PMID: 28122229