2023
Peripheral Center Sparing Presentation of Schnyder Corneal Dystrophy
Massimo Busin, Massimo M. Santoro, Jayne S Weiss Opthalmology. PMID: 37865907
The glucose-to-acetate metabolic flux that drives endothelial-to-mesenchymal transition via TGF-β signaling
Cristina Arte Recatalá, Massimo M. Santoro. Cell Metab. PMID: 37437542
Evaluation of post-natal angiogenesis in a mouse hind limb ischemia model
Cristina Arte Recatalá, Mattia Albiero, & Massimo M. Santoro. STAR Protocols PMID: 37437542
How to Generate a Vascular-Labelled Transgenic Zebrafish Model to Study Tumor Angiogenesis and Extravasation
Roxana E Oberkersch, Jacopo Lidonnici & Massimo M. Santoro. Methods Mol Bill PMID: 36161418
The circadian protein BMAL1 supports endothelial cell cycle during angiogenesis
Matteo Astone, Roxane E Oberkersch, Giovanni Tosi, Alberto Biscontin, Massimo M. Santoro Cardiovasc Res. PMID: 37052172
2022
YAP/TAZ-TEAD link angiogenesis to nutrients
Roxana E Oberkersch & Massimo M. Santoro. Nat Metab. PMID: 35726025
A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells
Brian G Coon, Sushma Timalsina, Matteo Astone, Zhen W Zhuang, Jennifer Fang, Jinah Han, Jurgen Themen, Minhwan Chung, Young Joo Yang-Klingler, Mukesh Jain, Karen K Hirschi, Ai Yamamato, Louis-Eric Trudeau, Massimo M. Santoro, Martin A Schwartz. J Cell Biol PMID: 35695893
Cancer-Induced Metabolic Rewiring of Tumor Endothelial Cells
Jacopo Lidonnici, Massimo M. Santoro, Roxana E Oberkersch. Cancers (Basel) PMID: 35681715
Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis
Roxana E Oberkersch, Giovanna Pontarin, Matteo Astone, Marianna Spizzotin, Liaisan Arslanbaeva, Giovanni Tosi, Emiliano Panieri, Sara Ricciardi, Maria Francesca Allega, Alessia Brossa, Paolo Grumati, Benedetta Bussolati, Stefano Biffo, Saverio Tardito & Massimo M. Santoro. Development Cell PMID: 35580611
UBIAD1 and CoQ10 protect melanoma cells from lipid peroxidation-mediated cell death
Liaisan Arslanbaeva, Giovanni Tosi, Marco Ravazzolo, Manuela Simonato, Francesco A Tucci, Salvatore Pece, Paola Cogo & Massimo M. Santoro. Redox Biology PMID: 35255427
Oxidative pentose phosphate pathway controls vascular mural cell coverage by regulating extracellular matrix composition
Nicola Facchinello, Matteo Astone, Matteo Audano, Roxana E. Oberkersch, Marianna Spizzotin, Enrica Calura, Madalena Marques, Mihaela Crisan, Nico Mitro & Massimo M. Santoro. Nature Metabolism PMID: 35102339
2021
LPHN2 inhibits vascular permeability by differential control of endothelial cell adhesion
Chiara Camillo, Nicola Facchinello, Giulia Villari, Giulia Mana, Noemi Gioelli, Chiara Sandri, Matteo Astone, Dora Tortarolo, Fabiana Clapero, Dafne Gays, Roxana E. Oberkersch, Marco Arese, Luca Tamagnone, Donatella Valdembri, Massimo M. Santoro* and Guido Serini*. Journal of Cell Biology PMID: 34581723
Origin and Mechanisms of Smooth Muscle Cells Development in Vertebrates
Michael Donadon and Massimo M. Santoro. Development PMID: 33789914
Efficient clofilium tosylate-mediated rescue of polg-related disease phenotypes in zebrafish
Nicola Facchinello, Claudio Laquatra, Lisa Locatello, Giorgia Beffagna, Raquel Brañas Casas, Chiara Fornetto, Alberto Dinarello, Laura Martorano, Andrea Vettori, Giovanni Risato, Rudy Celeghin, Giacomo Meneghetti, Massimo M. Santoro, Agnes Delahodde, Francesco Vanzi, Andrea Rasola, Luisa Dalla Valle, Maria Berica Rasotto, Tiziana Lodi, Enrico Baruffini, Francesco Argenton, and Natascia Tiso. Cell Death & Disease PMID: 33469036
Time to fight: targeting the circadian clock molecular machinery in cancer therapy
Matteo Astone and Massimo M. Santoro. Drug Discovery Today PMID: 33549826
Adaptive redox homeostasis in cutaneous melanoma
Liasian Arslanbaeva and Massimo M. Santoro. Redox Biology PMID: 33091721
2020
The Antioxidant Role of Non-mitochondrial CoQ10: Mystery Solved!
Massimo M. Santoro Cell Metabolism PMID: 31951565
Advantages and challenges of cardiovascular and lymphatic studies in zebrafish research
Massimo M. Santoro, Beltrame M., Panáková D., Siekmann A. F. Tiso, N., Venero Galanternik M., Hyun Min Jung and Brant M. Weinstein. Frontiers in Cell and Developmental Biology PMID: 31192207
Nano-sampling and reporter tools to study metabolic regulation in zebrafish
Thomas Dickmeis, Yi Feng, Maria Caterina Mione, Nikolay Ninov, Massimo M. Santoro, Herman P Spaink, Philipp Gut. Frontiers Cell and Developmental Biology PMID: 30873407
2019
Role of amino acid metabolism in angiogenesis
Roxana E. Oberkersch and Massimo M. Santoro. Vascular Pharmacology PMID: 30423448
Before the Pump
Dougall Norris and Massimo M. Santoro. Arteriosclerosis, Thrombosis, and Vascular Biology PMID: 30571178
2018
Loss of Pyruvate Kinase M2 Limits Growth and Triggers Innate Immune Signaling in Endothelial Cells
Oliver A. Stone, Mohamed El-Brolosy, Kerstin Wilhelm, Xiaojing Liu, Ana M. Romão, Elisabetta Grillo, Jason K.H. Lai, Stefan Günther, Sylvia Jeratsch, Carsten Kuenne, I-Ching Lee, Thomas Braun, Massimo M. Santoro, Jason W. Locasale, Michael Potente and Didier Y.R. Stainier. Nature Communications PMID: 33469036
Photobiomodulation at multiple wavelengths differentially modulates oxidative stress in vitro and in vivo
Rupel, K., Zupin, L., Colliva, A., Kamada, A., Poropat, A., Ottaviani, G., Margherita Gobbo, Lidia Fanfoni, Rossella Gratton, Massimo M. Santoro, Roberto Di Lenarda , Matteo Biasotto, and Serena Zacchigna. Oxidative Medicine and Cellular Longevity PMID: 30534349
LKB1 loss is associated with glutathione deficiency under oxidative stress and sensitivity of cancer cells to cytotoxic drugs and γ-irradiation
NZulato E., Ciccarese F., Agnusdei V., Pinazza M., Nardo G., Iorio E., Curtarello M., Silic-Benussi M., Rossi E, Venturoli C., Panieri E., Santoro M. Massimo, Quintieri L., Ciminale V, Indraccolo S. Biochem Pharmacology PMID: 30222967
Compound heterozygous loss-of-function mutations in KIF20A are associated with a novel lethal congenital cardiomyopathy in two siblings
Jacoba J. Louw, Ricardo Nunes Bastos, Xiaowen Chen, Céline Verdood, Anniek Corveleyn, Yaojuan Jia, Jeroen Breckpot, Marc Gewillig, Hilde Peeters, Massimo M. Santoro, Francis Barr, Koenraad Devriendt PLOS Genetics PMID: 2935759
New models to study vascular mural cell embryonic origin: implications in vascular diseases
Sanjay Sinha and Massimo M. Santoro Cardiovascular Research PMID: 29385541
Fashioning blood vessels by ROS signaling and metabolism
Massimo M. Santoro Seminars in Cell & Developmental Biology PMID: 28800930
2017
Real-time quantification of subcellular H 2 O 2 and glutathione redox potential in living cardiovascular tissues
Emiliano Panieri, Carlo Milia, and Massimo M. Santoro. Free Radical Biology and Medicine PMID: 28192232
Data on metabolic-dependent antioxidant response in the cardiovascular tissues of living zebrafish under stress conditions
Emiliano Panieri and Massimo M. Santoro Data in Brief PMID: 28516138
An exclusive cellular and molecular network governs intestinal smooth muscle cell differentiation in vertebrates
Dafne Gays, Christopher Hess, Annalisa Camporeale, Ugo Ala, Paolo Provero, Christian Mosimann, Massimo M. Santoro Development PMID: 28049660
Cilia Control Vascular Mural Cell Recruitment in Vertebrates
Xiaowen Chen, Dafne Gays, Carlo Millia, and Massimo M. Santoro Cell Reports PMID: 28122229